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In vivo toxicity of Chrysopogon aciculatus (Retz.) Trin. Extract in ICR mice.


Donaville Marie Ocampus,
Carol Franz Ocañada,
Saliha Mamaroba,
Sruthi Karumanchi,
Thigulla Thejaswi,
Anjana Chepella

Related Institution

College of Medicine - University of the Visayas - Gullas College of Medicine

Publication Information

Publication Type
Thesis Degree
Publication Date
May 2018


This study aims to evaluate the in vivo toxic effects of Chrysopogon aciculatus extract in ICR mice. Toxicity studies have been extensively researched for the toxic effects of many drugs and plants but not all have been comprehensively studied, especially Chrysopogon aciculatus, love grass. This study utilized an experimental research design involving two phases: the plant extract phase where the whole part of the plant (roots, stem and flowers) were used to obtain the extract and the experimental phase which comprised of two groups of ICR mice: 50 mice for the experimental group given plant extract and 10 mice for the negative control given distilled water. Based on the results there were no significant clinical signs and gross pathologic effects of Chrysopogon aciculatus extract in ICR mice. In conclusion, Chrysopogon aciculatus has no significant toxicity.


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Physical Location

LocationLocation CodeAvailable FormatAvailability
University of the Visayas - Gullas College of Medicine Library Fil.-T Oc12in 2018 Fulltext Print Format

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